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What are Radiopharmaceuticals?

Radiopharmaceuticals are a special class of drugs that contain
a radioactive isotope
Radiopharmaceuticals are a special class of drugs that contains a radioactive isotope

These radioactive isotopes emit energy, which can be detected using specialized scanners to
provide an image (diagnostic agent), or can be used for therapeutic applications and treatment of
disease (radiotherapeutic agent).

Millions of patients receive radiopharmaceuticals annually for a wide variety of medical procedures
ranging from the assessment of cardiac function, to neurological conditions, and the staging and
treatment of cancer.

These radioactive isotopes emit energy, which can be detected using specialized scanners to
provide an image (diagnostic agent), or can be used for therapeutic applications and treatment of
disease (radiotherapeutic agent).

Millions of patients receive radiopharmaceuticals annually for a wide variety of medical procedures
ranging from the assessment of cardiac function, to neurological conditions, and the staging and
treatment of cancer.

Diagnostics

Diagnostic agents are used for imaging
and determining site of disease,
treatment selection, and monitoring
response to treatment
Diagnostic agents are used for imaging and determining site of disease, treatment selection, and monitoring response to treatment
 When administered to a patient, the diagnostic probes
accumulate at the site of disease. These sites appear as
coloured or dark regions on a positron emission
tomography (PET) or single-photon emission computed
tomography (SPECT) scan. CPDC currently works with
partners to discover and develop next-generation
diagnostic radiopharmaceuticals, as well as bringing
diagnostics to Canada that were previously commercially
unavailable in the Canadian market.
When administered to a patient, the diagnostic probes accumulate at the site of disease. These sites appear as coloured or dark regions on a positron emission tomography (PET) or single-photon emission computed tomography (SPECT) scan. CPDC currently works with partners to discover and develop next-generation diagnostic radiopharmaceuticals, as well as bringing diagnostics to Canada that were previously commercially unavailable in the Canadian market.

Therapeutics

Therapeutic radiopharmaceuticals are
administered to a patient to selectively
seek out and deliver high energy
cell-killing radiation to the site of disease.
Therapeutic radiopharmaceuticals are administered to a patient to selectively seek out and deliver high energy cell-killing radiation to the site of disease.
 New therapeutic radiopharmaceuticals are being
designed to precisely target and kill cancer cells, while
sparing normal healthy tissue, and clearing rapidly from
blood and tissues. CPDC works with our partners to
discover and develop therapeutic radiopharmaceuticals
for unmet medical cancer needs.
New therapeutic radiopharmaceuticals are being designed to precisely target and kill cancer cells, while sparing normal healthy tissue, and clearing rapidly from blood and tissues. CPDC works with our partners to discover and develop therapeutic radiopharmaceuticals for unmet medical cancer needs.

Theranostics

Theranostic agents are complimentary
pairs targeting the same biomarkers or
disease where one
radiopharmaceutical can be used for
diagnosis and the other for therapy
with the only difference being the
radioisotope.
Theranostic agents are complimentary pairs targeting the same biomarkers or disease where one radiopharmaceutical can be used for diagnosis and the other for therapy with the only difference being the radioisotope.
Theranostics is a combination of diagnostic and therapeutic modalities. The imaging or therapeutic capability of a radioisotope depend on their method of decay (α, β (+/-), γ). Radioisotopes undergoing α or β (-) decay can be used for therapy while those undergoing β(+) or γ decay can be used for imaging (diagnosis). Theranostic pairs used in the clinic currently include 125I/131I , 68Ga/177Lu, and 99mTc/223Ra amongst others. CPDC works with our partners to discover and develop theranostic agents to further personalized medicine.
Theranostics is a combination of diagnostic and therapeutic modalities. The imaging or therapeutic capability of a radioisotope depend on their method of decay (α, β (+/-), γ). Radioisotopes undergoing α or β (-) decay can be used for therapy while those undergoing β(+) or γ decay can be used for imaging (diagnosis). Theranostic pairs used in the clinic currently include 125I/131I, 68Ga/177Lu, and 99mTc/223Ra amongst others. CPDC works with our partners to discover and develop theranostic agents to further personalized medicine.